Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 14th World Congress on Healthcare & Technologies | London, UK.

Day 1 :

Keynote Forum

Sean Hall

Medlab Clinical LTD, Australia

Keynote: Potentiating new neurological pain drugs from cannabis (CBD/THC)

Time : 09:15-10:00

Conference Series Healthcare Summit 2019 International Conference Keynote Speaker Sean Hall photo
Biography:

Sean Hall is the MD and Chief Executive Officer at Medlab Clinical LTD, Sydney, Australia. He founded Medlab in August 2012. He has over 20 years’ experience in nutraceutical sales and development, as well as early drug discovery in Australia, Asia and the US. He has led and inspired his teams to author multiple patents, write peer reviewed articles and deliver lectures at scientific conferences. His passion is leading his researchers into novel areas and strong commercialisation opportunities. He was a founder of FIT-BioCeuticals. For his sale of FIT-BioCeuticals to Blackmores in 2012, he was nominated as a finalist in the inaugural Australian Exit CEO of the Year Award. He is a Medical Doctor with an MBA in Clinical Pharmaceutical Management, and focuses on the research to pioneer innovation and commercialisation. He is an active member of Medicines Australia, the European Medical Association, the American Federation for Medical Researcher, The World Medical Association, A4M and Special Operations Medical Association.

Abstract:

Neurology is a complex area, potentially requiring a combination of surgical and non-surgical intervention. Regardless of the intervention plan, neurology is hindered with a number of co-morbidities that can diminish patient outcomes, one in particular is pain. Pain management requires a number of pharmaceutical agents principally from the opioid class of drugs, potentiating heightened secondary organ toxicity profiles. Further it is accepted that some 33% + of patients undergoing chemotherapy will state that their pain is under-managed. Cannabinoids potentiate new treatments in pain management and posit opioid reduction. Theoretically, the argument appears sound; in real world practice, cannabinoid preparations differ vastly ultimately affecting the efficacy of the final product. This presentation will take a first-hand look at Medlab’s work into developing a standardised and validated “early” drug used in clinical trial and suited for Regulatory (TGA, FDA, EMA) acceptance.

Keynote Forum

Becky Faett

University of Pittsburgh, USA

Keynote: Driving innovation through a collaborative simulation supported telehealth initiative

Time : 10:00-10:45

Conference Series Healthcare Summit 2019 International Conference Keynote Speaker Becky Faett  photo
Biography:

Becky Faett has been a Full Time Faculty Member at the University of Pittsburgh, School of Nursing since 2006. She has received her PhD in Rehabilitation and Technology from the University of Pittsburgh. Her research focuses on enhancing functional ability and self-management of those disabled by chronic illness. Her dissertation for her PhD involved the development, implementation and evaluation of the education component of a tele-rehabilitation program designed to enhance functional ability and self-management of individuals with limited mobility due to lymphedema. She has received multiple awards for her innovative teaching including the Provost’s Innovation in Education award, the Distinguished Clinical Scholar award, the Nursing Excellence in Teaching and Technology award and the Dean’s Distinguished Teaching award.

Abstract:

Numerous studies demonstrate the delivery of care through telecommunications is effective. With reimbursement a reality, the growth of telehealth will be exponential. Simulating telehealth is a critically necessary, safe, and effective process that prepares students for the present and the future delivery of health care. Operationalize the complexities of remote care requires practice. This initiative explores the intricacies of launching a sustainable telehealth simulation symposium with faculty new to simulation while studying the impact on students’ knowledge, skills and attitudes. Using best practice standards this innovation supports faculty teaching in a challenging new environment while cultivating student’s clinical judgment outside of the clinical arena. The design, based on course objectives and university level nursing essentials, provided structured evidenced based simulation that enabled students to recognize and implement best practices in assessment, remote intervention, self-management education and caregiver support. 140 students practiced telehealth from both the urban clinician and rural caregiver vantage. Significant difference with moderate to large effect size were found in the students’ self-evaluation regarding communication strategies, assessment with sensory limitations, remote intervention, self-management education, and caregiver support. Focus group methodology was used to evaluate the telehealth simulation sceneries. 10% of students who participated in the project were asked to provide evaluation data. Content analysis was used to identify themes and used to refine the structure and content of the simulation sessions. Three themes; the challenges, the imperative to teach well with ever patient contact, and creative problem solving was identified in focus groups. Future practice is planned with at-risk new mothers in the junior year and studying long term retention in the senior year.

Conference Series Healthcare Summit 2019 International Conference Keynote Speaker Denise M Breadsell  photo
Biography:

Denise Breadsell qualified as a Registered Nurse in Queensland in 1982 and a Registered Midwife in Queensland in 1985 and has gained a breadth of experience in nursing and midwifery across rural, remote and urban areas. She has worked across public, private and aged care sectors, predominantly in Queensland, Australia during the past 40 years. Her areas of practice have included; Public Health Nurse – Communicable Diseases/Immunization, Sexual and Reproductive Health Nurse, Midwifery, Infection Control, Tuberculosis management, Refugee and Indigenous Health, Quality Management, Nurse Education, Operating Theatre, School Based Youth Health Nurse and Orthopedics, before starting work with the Queensland Nurses and Midwives’ Union (QNMU) 5 years ago as a Professional Officer responsible for codes and standards of practice. She has obtained tertiary qualifications including; a degree in Health Science Nursing Southern Cross University; a Graduate Certificate Infection Control Griffith University, a Masters in Public Health Newcastle University.

Abstract:

Queensland is Australia’s most geographically decentralised state with regional centres located throughout, as well as many isolated communities.  The Rural and Isolated Practice Endorsed Nurse (RIPEN) is particularly effective in this environment providing emergency and primary healthcare, working in rural hospitals, mining sites, indigenous communities, tourist resorts, remote pastoral stations where onsite access to medical practitioners and/or nurse practitioners is by visit only or not available at all and to rural and remote area emergency sites. The Nursing and Midwifery Board of Australia has advised the RIPEN endorsement for scheduled medicines for registered nurses to supply under protocol will be discontinued, once reliant states and territories have developed and implemented viable alternatives. The Queensland Nurses and Midwives’ Union (QNMU) has a long history of collective professional activism by members to achieve improved working conditions. This presentation will describe the collective professional activism initiatives undertaken by QNMU RIPEN members to maintain access and coverage of health services. This will include navigation through negotiations with key stakeholders across state and national jurisdictions to achieve a viable alternative to the RIPEN model of care for people living in rural and isolated communities in Queensland

  • Healthcare | Healthcare and Technology | Digital Health | Healthcare and Nursing | E-health
Location: Johnson
Speaker

Chair

Sean Hall

Medlab Clinical LTD, Australia

Speaker

Co-Chair

Becky Faett

University of Pittsburgh, USA

Session Introduction

Florea Scarlat

National Institute for Laser, Plasma and Radiation Physics, Romania

Title: Basic principles in conventional and laser driven therapy accelerators
Speaker
Biography:

Florea Scarlat has completed his Graduation as a Physicist Engineer from the Faculty of Electronics and Telecommunications at the Polytechnic University of Bucharest, Romania. Later on he obtained his PhD in Nuclear Techniques at the Institute of Atomic Physics of the State Committee for Nuclear Energy with subjects “Contributions to the development of the magnetic induction electron circular accelerator for radiotherapy use”. He was the Scientific Director at the Institute of Physics and Nuclear Engineering Bucharest, Magurele and Director of the Romanian-English joint venture GEC Romanian Nuclear Limited, Leicester, England. Then he was a fulltime Professor of Physics at Valahia State University of Targoviste. He was elected Member of the New York Academy of Sciences and Corresponding Member of the Romanian-American Academy. Currently, he is a Consultant Manager at STARDOOR Laboratory at the National Institute for Lasers, Plasma and Radiation Physics, Magurele

Abstract:

Radiation beams used in therapy for a malignant tumor treatment located in a patient's body, should meet two conditions: 1. to have sufficient energy to penetrate to the depth of the tumor; and 2. the radiation intensity after equalization on the radiation field at the entrance to the tumor to provide the energy absorbed per unit mass of 2 Gy per session. The paper presents the principles of electromagnetic acceleration of leptons and hadrons used in radiotherapy. Particle beams are provided by conventional accelerators based on the principle of electromagnetic acceleration in the field of radiofrequency, non-resonant (betatron and betatron linear), resonant with cavities (microtron, isochronous cyclotron, synchro-cyclotron and synchrotron) and resonant with waveguides (linac). Conventional accelerators based on radiofrequency technology have the deficiency of a relatively low acceleration gradient which leads to a small ratio between the length of the acceleration space and the length of the trajectory traveled by the beam. In order to increase this ratio and to reduce the weight of the accelerator, the superconducting magnets technology was used. Acceleration principles for new models of accelerators are presented: fixed field alternating gradient accelerator (FFAG) - a combination of cyclotron and synchrotron, dielectric wall accelerator (DWA), which is the type of conventional induction accelerator and dielectric laser accelerator (DLA) - which instead of radiofrequency waves it uses a laser beam to generate electric fields for accelerating in the dielectric structure. The disadvantage of RF waves about acceleration gradient is removed by using the relativistic mode when laser provide a peak amplitude of the transverse electric field of a linear polarized laser pulse greater with about four orders of magnitude. The principles of laser acceleration of electrons, gases and plasmas and the principles of acceleration TNSA and RPA for hadrons are presented.

Periasamy Parikumar

The Light Eye Hospital, India

Title: Blood vessel sample from the conjunctiva of the eye

Time : 12:15-12:40

Speaker
Biography:

Periasamy Parikumar is an ophthalmologist and a stem cell researcher. He owns an Indian patent and a US patent. He has performed about 30,000 intraocular lens implantation surgeries and has taken part in several eye camps and eye donation activities. He has published several papers on Stem cell research in the national and international journals like Indian Journal of Ophthalmology, American Journal of Stem Cells and PubMed

Abstract:

We diagnose a person’s health by examining the pulse & blood. We just examine the content and ignore the container. Here we are coming up with a concept where we could take a blood vessel sample, in addition to the blood sample, which alone would give a person’s total health information. The Virchow’s triad speaks of endothelial cell damage, which we have missed out for more than a century. Here we propose a personalized evaluation of a person’s health by correlating both the blood sample report and the Blood Vessel Sample report. The only part of the body from which we can safely collect a Blood Vessel Sample is the conjunctiva of the eye. An Ophthalmologist will take out a couple of millimeters of blood vessel sample from the conjunctiva with ease as an outpatient procedure. The endothelium is then expanded and subjected to a battery of biochemical investigations like Nitric oxide production capacity, VEGF etc and histopathological examinations. The kit containing instruments needed to collect the Blood Vessel Sample is patent protected. The standard operating procedure is patent & copyright protected. The new terminologies we propose are blood vessel sample, blood vessel sample kit, vascular endothelial response to diabetes, diabetic conjunctival vasculopathy, invisible vascular web, visible vascular web, supra tenon vascular web and infra tenon vascular web. Hence a person’s health is determined and diagnosed only by evaluating both the blood sample and the blood vessel sample. This procedure is not only limited to diagnostic purposes but could be used as a therapeutic method to treat the micro vascular diseases. This will pave way for a paradigm shift in treating metabolic syndromes, micro vascular and macro vascular diseases.

Speaker
Biography:

Manisha Bhatt Dwivedi is working as a Professor of Anesthesiology, in the Department of Anesthesiology and Critical Care MMIMSR Mullana, Ambala, India. Her areas of interest are airway management, life support programs and neuromuscular monitoring. She is regularly organizing and participating in the workshops related to these skills and is engaged in teaching and training programs as incharge simulation laboratory, central research cell

Abstract:

Statement of the Problem: After laparoscopic cholecystectomy somatic pain due to incisions given on the skin at the port site plus visceral pain from organs in the abdominal cavity and shoulder pain due to irritation of the diaphragm are the constant annoying factors. To reduce this pain a wide range of analgesic drugs and anti-inflammatory drugs have been introduced-glucocorticoids being one of them can decrease convalescence period if used preoperatively.

Aim: In this study we evaluated whether preoperative intravenous dexamethasone is effective enough to decrease postoperative pain of laparoscopy cholecystectomy and improve quality of recovery in postoperative period.

Methodology: The study was conducted on 50 patients randomly divided by envelope draw method into two groups of 25 each. All belonged to ASA-I and ASA-II. Patients of group A were given 2ml I/V normal saline as placebo and to patients of group B I/V dexamethasone 8 mg (2ml) was given 90 minutes before induction of anesthesia. Post-operative pain was assessed at rest and during mobilization at equal interval of time according to visual analog scale (VAS) and verbal rating scale (VRS). CRP levels and postoperative requirement of rescue analgesic were also noted.

Findings: Dexamethasone significantly reduced postoperative pain during the first 24 postoperative hours .The added total VAS and VRS score of first 24 hours post-op for overall pain at rest [placebo (VAS-108, VRS-102) and dexamethasone group (VAS-56, VRS-60)] and during mobilization [placebo (VAS-125, VRS-129) and dexamethasone group (VAS-66, VRS-66)] were significantly low in dexamethasone group and overall requirement of analgesic was also decreased in dexamethasone group than placebo group in first 6 post-operative hours. (P-value=0.001). CRP levels were significantly low in dexamethasone group than placebo group (P value=0.0001).

Conclusion & Significance: Pre-operative I/V administration of 8mg dexamethasone 90 minutes prior to induction of anesthesia for laparoscopic cholecystectomy surgery provide effective postoperative analgesia and reduce need for rescue analgesics.

Speaker
Biography:

Ala Szczepura has an established track record in health technology assessment (HTA) with over thirty years’ experience in policy research and economic evaluation in health care. She has specific research interests in evaluation of new and emerging technologies; re-design, delivery and assessment of digital services; and provision of services to meet the needs of diverse populations. She has published over 150 peer-reviewed scientific articles in these areas, and has been actively involved in development of the NHS R&D programme since its inception. She currently holds a Cross-Faculty Chair at Coventry University with the aim of strengthening interdisciplinary research to address key future technological challenges for health and social care services. She was the winner of the 'Services to Medicine' category in the First English Women's Awards 2018.

Abstract:

Statement of Problem: Acute onset facial nerve paralysis (FNP) is the most common disorder affecting a single nerve. This distressing neurological condition means patients lose the ability to move facial muscles on the affected side of the face. Overall, one in 60 individuals (usually aged 30-will be affected over the course of their lifetime. Evidence on effective intervention, apart from drug therapy within 72 hrs, supports the benefits of tailored facial exercise (TFE) therapy. Smart wearables (FRAME emerging technology) consisting of spectacles with miniaturized sensors to measure facial movement, linked to a smartphone, could potentially improve TFE delivery by specialist centers. A major National Institute of Health Research study is reported.

Methodology & Theoretical Orientation: HTA study to model costs and benefits of introduction of this emerging technology. Stages included: estimation of size of problem; updated systematic review of effectiveness of physical therapy; three national surveys (medical staff, facial therapy specialists and patients) to gather data on current treatment pathways and access to TFE therapy; Delphi Exercise to identify consensus on key outcomes and technology introduction; economic modeling.

Findings: 22,500 FNP cases annually in the United Kingdom (UK), cumulative number since 2000 over 427,000; TFE can improve facial function for moderate paralysis and chronic cases and reduce sequelae in acute cases; only 17% of eligible UK patients currently access personalized TFE therapy, with patients traveling up to 200 miles; Delphi panel identified important patient benefits from this emerging technology but also barriers to introduction and economic modeling confirms potential for cost-effective introduction.

Conclusion & Significance: This emerging wearable technology could make a major difference to FNP patients’ lives, as well as generating potential efficiencies for healthcare. Findings from this study will inform the final design and introduction of this technology.

Speaker
Biography:

Ritesh Chaudhary has completed three-year course of Doctor of Medicine (MD) in General Practice and Emergency Medicine in 2012 and eighteen months course of Post Graduate Fellowship in Emergency Medicine in 2017. His expertise is in evaluation and passion in improving the health and well-being. His research based on use of Smartphones in medical education and practice creates new pathways for improving healthcare. He has built these concepts in research and teaching both in hospital and education institutionshttps://europe.healthconferences.org/events-list/healthcare-and-sociology

Abstract:

Statement of the Problem: Smartphone has emerged common place within the medical field as both a personal and professional devices. Most health care experts desire current clinical facts and decisions that support at the point of patients’ care. Double-check recommendations with scientific apps and additional researches may add benefits towards patients’ greatest satisfaction in medical care.We therefore, like to ascertain the use of Smartphones in medical education and practice among medical officers, residents and faculties of Emergency department of BP Koirala institute of Health Sciences (BPKIHS), Nepal.

Methodology & Theoretical Orientation: A cross-sectional study done in all the medical officers, residents and faculties working in Emergency ward and GP OPD of Department of General Practice and Emergency Medicine at BPKIHS.

Findings: Interviews were conducted with one hundred (100) participants (51% residents, 33% medical officers and 16% faculty members). Over 99% of participants reported using smartphones and 89% of participants used smartphones over more than two years. 55% bought smartphone to use in medical education and 98% of participants found using medical apps in clinical practice. 99% believed that smartphone apps were supportive to learning especially in clinical exam tests and findings 75%. Ninety-six (96%) of the participants believed the concept of smartphones was useful. 66% of respondents expressed their views regarding smartphone use in medical education in future endeavors.

Conclusion & Significance: The study confirms that smartphones are ubiquitously adopted by residents and medical officers and faculty members in medical education and practice at our institute

Speaker
Biography:

John Momoh specializes in project management and field operations. He currently manages the tracking project and the field operations teams in Borno, Nigeria.

Abstract:

Statement of the Problem: Health workers are required to visit every settlement location and vaccinate all eligible children during polio immunization campaigns. Several factors pose challenges to reaching every settlement are missed during immunization campaigns, especially in Borno Nigeria. Some of these are: (1) Settlements lists at the state do not correlate to those at the local government areas (LGA); (2) Settlements missed were reported at the end of the campaign with visits planned for a mop-up day; (3) The security situation in Borno is volatile, this sometimes leads to changes in the daily implementation plan (DIP) at the LGA, which leaves a large number of settlements missed at the end of the campaigns.

Methodology: As part of the development of a solution to optimize planning, tracking and reporting of health interventions activities, we developed a tool to support dynamic planning, enabling changes in DIPs at LGA due to fluctuating security situations and logistics challenges to be incorporated into the daily monitoring of settlement visits. Finally, the tool enabled analysis of visitation results, visual presentation and automated generation of visitation maps to support daily reviews and decision making by government and health workers.

Findings: This tool analyzes and compares GPS coordinates from mobile devices carried by vaccination teams against those of settlements on the DIP to generate a map and list of settlements visited or missed on a daily basis. Field consultants at the LGAs review meetings, which aid the teams to plan visits to missed settlements on subsequent days prior to the final mop up day.

Conclusion & Significance: Proportion of settlements missed after a campaign has significantly reduced from 22% to 1% and proportion of missed settlements resolved before the end of campaign increased from 8% to 49% in November 2017 and March 2019 respectively.

Speaker
Biography:

Antoine Vikkey Hinson is an Occupational Health Practitioner, Senior Lecturer in Occupational Health at the University of Abomey-Calavi in Benin. As an expert with the WHO support, he is engaged in health wise training in Togo, in Benin and in French speaking countries. He also built his expertise in informal sector mainly with the pesticide exposure of the farmers. He wrote many papers in air pollution

Abstract:

Aim: The aim of the study was to have a better understanding of the sleep-related diseases suffered by workers of the National university hospital center-HKM (CNHU-HKM), reference Hospital.

Methods: It was a descriptive, cross-sectional study that involved 298 CNHU-HKM workers randomly selected from the 1048 agents of the hospital. It lasted from 1 July to 30 September 2016. The data collected was stripped and captured using Epidata software and statistical analyses with SPSS.17.0 software.

Results: The average age of the sample was 37.8 years 0.6 with 55.7% of men. The prevalence of chronic debt of sleep was 67.1% and 14.8% of those workers took medication to facilitate occurrence of sleep. 66.8% were sleepless. Several factors are associated with insomnia; alternate shift workers had more insomnia than fixed shift workers (p=0.04); workers had great difficulty concentrating (p=0.04) and excessive daytime fatigue (p=0.002). For the Obstructive sleep apnea-hypopnea syndrome (OSAHS), its frequency was 23.5%. This frequency increased with age. The female sex was dominant: 32.9% in the evocative symptoms of OSAHS. The factors associated with this were: the antecedent of high blood pressure OR=2.37 (IC 95% [1.02-5.52]), the consumption of a lot of alcohol OR=4.12 (IC 95% [1.03; 16.46]). Associated factors with this were: the antecedent of high blood pressure OR=2.37 (IC 95% [1.02-5.52]), the consumption of alcohol OR=4.12 (IC 95% [1.03; 16.46]).

Conclusion: Sleep disorders remain a pathology to which very little attention is given in the health care system and especially in professional fields in Benin. The present study is now shedding light on it back in order to encourage the development of national and adapted control strategies to reduce the drawbacks of that on the country's economy.

Speaker
Biography:

Chiu-Ping Cho is an RN, Hemodialysis and a Head Nurse at Chi Mei Medical Center, Taiwan. Her research interest focus on hemodialysis, physician, nephrology

Abstract:

Background: The incidence and prevalence rate of dialysis patients in Taiwan ranks first in the world, and the annual health insurance budget is more than 30 billion Yuan. Dialysis is a lengthy treatment process that often results in major changes in the quality of life of patients and their families. If the patient enters dialysis without being prepared, it will increase the risk of death from heart and lung failure or infection, in addition to increasing the medical burden and affecting the quality of life.

Aim: Chronic kidney disease enters end-stage renal failure. At this time, in addition to giving patients psychological support, medical staff can use shared decision-making to discuss dialysis mode with family and friends, in order to jointly achieve the best feasible treatment options.

Case: From November 14, 2017 to December 31, 2018, there were 82 patients with stage 4 or 5 chronic kidneys (eGFR≦15~29ml/min/1.73m2).

Method: The quality research method has been designed to accept cases. In the patient clinic or during the period, when the patient chooses to take care of the team from the nephrology team, he will launch the “dialysis mode selection method for medical and disease sharing decision-making” to enhance the diversity of the teaching aids. In combination with the concept of empirical care and the use of shared decision-making techniques, we provide an aid tool physical model and a medical decision-sharing manual, and use filming, editing, integration and PPT file production to make "end kidney disease patients. Which dialysis should I choose? The health education film fully provides information on the dialysis treatment methods of patients and their families.

Outcome: When patients and their families are hospitalized or return home, they can watch multimedia animations online. 81% of patients have confirmed dialysis mode, 79% of them choose hemodialysis, and 21% choose peritoneal dialysis. Satisfaction with results is 99%.

Conclusion: Use shared decision-making to provide information about the end-stage renal disease dialysis model, so that when you are faced with the choice of dialysis mode, you can make the most appropriate treatment decisions for yourself and your family, and implement the “information selection, confirmation communication and mutual respect”.

Sylwia Baluta

Wroclaw University of Science and Technology, Poland

Title: Biosensors-Novel devices for point-of-care (POC) testing
Speaker
Biography:

Sylwia Baluta has completed her Graduation in the field of Biotechnology and Medicinal Chemistry at Wroclaw University of Science and Technology. Since 2015, she is a PhD student at Wroclaw University of Science and Technology, Faculty of Chemistry. Her scientific interests include enzyme-based sensors for neurotransmitters determination, based on electrochemical and optical measurements. In 2018, she received a Minister of Education scholarship for outstanding scientific achievements

Abstract:

The evolution of biosensors was driven by the need for faster and more versatile analytical methods for application in important areas including clinical, diagnostics, food analysis or environmental monitoring, with minimum sample pretreatment. Rapid and sensitive neurotransmitters detection (i.e. epinephrine, dopamine, norepinephrine) is extremely important in modern medicine. These compounds mainly occur in the brain and central nervous system of mammals. Any changes in the neurotransmitters concentration may lead to many diseases, such as Parkinson’s or schizophrenia. However, there is any available device, which will show concentration of these compounds in patient’s body. Classical techniques of chemical analysis, despite many advantages, do not permit to obtain immediate results or automatization of measurements. Chemical sensors have displaced the conventional analytical methods-sensors combine precision, sensitivity, fast response and the possibility of continuous-monitoring. Our research is focused to develop optical and electrochemical biosensors or sensors for neurotransmitters detection. In developed optical biosensor for detection of dopamine, we used graphene quantum dots (GQDs) for detection system. In such sensor dopamine molecules coats the GQD surface-in result occurs quenching of fluorescence due to Resonance Energy Transfer (FRET). Changes in fluorescence correspond to specific concentrations of the neurotransmitter in tested sample, so it is possible to accurately determine the concentration of dopamine in the sample. Our research also has proved facile and convenient method for epinephrine, norepinehrine and also dopamine determination based on laccase and tyrosinase-based oxidation of catecholamine derivatives. The resulting sensors (built of electrode modified with graphene quantum dots or semiconducting polymer and laccase) exhibit good performance, strong affinity between enzyme and neurotransmitter, fast response to the substrate and good linear range. Such systems could be used in medical diagnostics for neurotransmitters detection